Alzheimers Clinical Trials
Alzheimers Clinical Trials
Alzheimers disease is the most common cause of dementia in elderly people. Currently, there is no way to prevent the disease or a cure for it. However, there are several Alzheimers clinical trials being run in many different research facilities in the United States and in other parts of the world. It is said that there are almost 1000 Alzheimers clinical trials been done in the United States alone.
Clinical trials can be defined as research in human health. These trials have to follow a set protocol. The protocol spells out the research parameters, the kind of people to be included in the clinical trial, the duration of the trial, the schedule for testing, type of medications to be used and their dosage and so on. The aim of the protocol is to get answers to research questions and to protect the Alzheimers clinical trials volunteers.
Alzheimers clinical trials are generally open to both people suffering from the disease and those who are not. The Alzheimers clinical trials are however being encumbered by the lack of people coming forward as volunteers for the trials. Most of the participants in these types of clinical trials are people who have already being diagnosed with the disease and are hoping to get access to the latest developments in Alzheimers disease research. These are people willing to try out experimental drugs which have not yet been approved by the FDA (Food and Drug Administration) for marketing to the mass market. The FDA must however approve any drugs that will be used for human testing.
Alzheimers clinical trials are of different types which depend on the research team’s approach and interest. The clinical trials are basically of 5 types; prevention trials (interest is to find ways to prevent the disease from happening and it is during this type of trials that vaccines are discovered), treatment trials (these types experiment with new drugs and new surgical methods), diagnostic trials (aim is to find better and more efficient ways of diagnosing the disease), supporting care trials (these trials aims to find ways to improve the quality of life of people with the disease) and screening trials (these aim to find ways to find people more prone to getting the disease).
Alzheimers clinical trials are also conducted in phases. These phases are designed to help answer specific research questions. There are 4 phases. The first 3 phases are differentiated by the number of clinical trial participants. The number gets progressively larger at each phase. For example, a phase 1 clinical trial will have a small number of volunteers, usually not exceeding 100. In phase 2, the number will rise to about 300. Phase 4 may include up to 3000 participants. Phase 4 is the stage just before FDA approval and is used to determine risks of the drug and the best way to use it.
Since there is not yet a cure for Alzheimer’s it would be good for anyone who is caring for or watching over an elderly individual to look for early Alzherimer’s warning signs. Though there is no cure there are ways to slow it down. We hope this article on Alzheimers clinical trials has been interesting and helpful.